|
KMID : 0388420000100010167
|
|
Konkuk Journal of Medical Sciences
2000 Volume.10 No. 1 p.167 ~ p.173
|
|
|
A Case of Subacute Combined Degeneration in Patient with Total Gastrectomy
|
|
Han Jeong-Ho
Ha Hyun-Wook
Lee Chung-Seok
Song Eun-Hyang
Kim Woo-Jeong
Kim Doo-Eung
Choi Jin-Young
|
|
|
Abstract
|
|
|
|
Subacute combined degeneration is a metabolic disorder of the spinal cord caused by vitamin B12 deficiency. A 72-year old man was admitted with weakness and tingling sensation of the both upper extremities. 9 years ago, he was diagnosed as having stomach cancer. So total gastrectomy with splenectomy was done at that time. The complete blood cell counts and morphology revealed megaloblastic anemia. Nerve conduction velocity study(NCV), electoromyography(EMG) and somatosensory evoked potentials(SEP) showed diffuse sensorimotor peripheral neuropathy. Magnetic resonance imaging(MRI) showed an increased T2-weighted signal, mild decreased Tl-weighted signal, and slight contrast enhancement of the posterior columns of the cord in the cervical and upper thoracic spinal region. He was treated with vitamin B12 supplements and improved gradually. If abnormal sensation and muscle weakness was developed after gastrointestinal surgery, subacute combined degeneration should be considered in the differential diagnosis. We describe MRI findings of a typical case of subacute combined degeneration, which was induced by total gastrectomy.
|
|
|
KEYWORD
|
|
|
vitamin B_(12) deficiency, subacute combined degeneration, MRI
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|